Sometimes the error only occurs in fullscreen. Force windowed mode, then switch back in-game.
"Serious Sam 3: BFE" is known for its chaotic action and massive battles, but many players have had their experience halted immediately upon launch by a frustrating error message: This usually indicates that the game is trying to launch with a screen resolution or refresh rate that your monitor does not support. serious sam 3 cannot set display mode
Sometimes the problem isn't the game but a broken DirectX installation. Sometimes the error only occurs in fullscreen
Windows display scaling sometimes blocks the game from accessing full-screen permissions. serious sam 3 cannot set display mode
If you're using Steam, you can bypass the bad settings by forcing a standard, universally supported resolution.
You can bypass initial configuration errors by forcing resolution through the Steam Launcher .