The ePSXe community and documentation are valuable resources. There might be specific advice or fixes for the game you're trying to play.
: If the emulator crashes once, it may leave a "hung" process running in the background. Check your Task Manager or restart your computer to clear the memory before trying again. Recommended Alternative epsxe core stopped check the section 316
Try another game: If other games work, the specific ISO or ROM you are using is likely damaged. The ePSXe community and documentation are valuable resources