The most compelling phase of Manthra’s career is her current one, where she actively deconstructs her "sister" image. In recent television serials and films, she plays .

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During her peak in the late 1990s, Manthra was a sought-after heroine across the Tamil and Telugu film industries, often cast in quintessential romantic and family dramas. Breakthrough Pairings

In her early career, she was celebrated for portraying soft-spoken, family-oriented roles in dramas.

: She gained significant recognition for her role in the Telugu film Gokulamlo Seetha (1997) and the romantic drama Subhakankshalu (1997), which showcased her versatility.

Manthra has been linked to several actors and celebrities in the Tamil film industry. Some of her notable relationships include: