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(sufficient space and proper facilities).

Using fewer animals to obtain the same amount of data. (sufficient space and proper facilities)

Animal Welfare and Rights: Navigating the Ethics of Our Relationship with Non-Human Animals They are "subjects of a life"—they have preferences,

The philosophical position of animal rights (most famously argued by Tom Regan and Peter Singer) holds that animals are not ours to use. They are "subjects of a life"—they have preferences, memories, and a desire to continue living. Using a sentient being as a resource (even if you do it "nicely") is considered a form of exploitation. The day they released him, Silas didn't bolt

Here is where the conversation gets tricky—and important.

The day they released him, Silas didn't bolt. He stood at the edge of the transport crate, his nose twitching. He stepped onto the grass, and his legs trembled—not from the chain, but from the terrifying softness of the earth.