Five of the world’s best fighters receive mysterious invitations to participate in a secret fighting tournament called the “Dead or Alive” competition, held on a remote island owned by the enigmatic Donovan. The fighters—Kasumi (Devon Aoki), Hitomi (Holly Valance), Tina Armstrong (Jaime Pressly), Christie Allen (Sarah Carter), and Helena Douglas (Sarah Carter’s character arc)—must battle each other in spectacular martial arts combat while uncovering a dark secret about the tournament organizers.